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The combined effect of obesity and aging on human sperm DNA methylation signatures: inclusion of BMI in the paternal germ line age prediction model

Male aging and obesity have both been shown to contribute to declines in fertility in men. Recent work in aging has shown consistent epigenetic changes to sperm as a man ages. In fact, our lab has built a tool that utilizes DNA methylation signatures from sperm to effectively predict an individual’s...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Salas-Huetos, Albert, James, Emma R., Broberg, Dallin S., Aston, Kenneth I., Carrell, Douglas T., Jenkins, Timothy G.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7506015/
https://ncbi.nlm.nih.gov/pubmed/32958862
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-71979-8
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