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Age-Associated Sperm DNA Methylation Alterations: Possible Implications in Offspring Disease Susceptibility

Recent evidence demonstrates a role for paternal aging on offspring disease susceptibility. It is well established that various neuropsychiatric disorders (schizophrenia, autism, etc.), trinucleotide expansion associated diseases (myotonic dystrophy, Huntington's, etc.) and even some forms of c...

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Detalhes bibliográficos
Main Authors: Jenkins, Timothy G., Aston, Kenneth I., Pflueger, Christian, Cairns, Bradley R., Carrell, Douglas T.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4091790/
https://ncbi.nlm.nih.gov/pubmed/25010591
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1004458
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