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Arrhythmogenic Mechanisms in Heart Failure: Linking β-Adrenergic Stimulation, Stretch, and Calcium

Heart failure (HF) is associated with elevated sympathetic tone and mechanical load. Both systems activate signaling transduction pathways that increase cardiac output, but eventually become part of the disease process itself leading to further worsening of cardiac function. These alterations can ad...

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Detalhes bibliográficos
Publicado no:Front Physiol
Main Authors: Johnson, Daniel M., Antoons, Gudrun
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6196916/
https://ncbi.nlm.nih.gov/pubmed/30374311
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphys.2018.01453
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