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Arrhythmogenic Mechanisms in Heart Failure: Linking β-Adrenergic Stimulation, Stretch, and Calcium

Heart failure (HF) is associated with elevated sympathetic tone and mechanical load. Both systems activate signaling transduction pathways that increase cardiac output, but eventually become part of the disease process itself leading to further worsening of cardiac function. These alterations can ad...

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Pubblicato in:Front Physiol
Autori principali: Johnson, Daniel M., Antoons, Gudrun
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2018
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6196916/
https://ncbi.nlm.nih.gov/pubmed/30374311
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphys.2018.01453
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