Proinsulin C-peptide is an autoantigen in people with type 1 diabetes

Type 1 diabetes (T1D) is an autoimmune disease in which insulin-producing beta cells, found within the islets of Langerhans in the pancreas, are destroyed by islet-infiltrating T cells. Identifying the antigenic targets of beta-cell reactive T cells is critical to gain insight into the pathogenesis...

詳細記述

保存先:
書誌詳細
出版年:Proc Natl Acad Sci U S A
主要な著者: So, Michelle, Elso, Colleen M., Tresoldi, Eleonora, Pakusch, Miha, Pathiraja, Vimukthi, Wentworth, John M., Harrison, Leonard C., Krishnamurthy, Balasubramanian, Thomas, Helen E., Rodda, Christine, Cameron, Fergus J., McMahon, Jacinta, Kay, Thomas W. H., Mannering, Stuart I.
フォーマット: Artigo
言語:Inglês
出版事項: National Academy of Sciences 2018
主題:
Biological Sciences
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6196477/
https://ncbi.nlm.nih.gov/pubmed/30275329
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1809208115
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