Preservation of myocardial contractility during acute hypoxia with OMX-CV, a novel oxygen delivery biotherapeutic

The heart exhibits the highest basal oxygen (O(2)) consumption per tissue mass of any organ in the body and is uniquely dependent on aerobic metabolism to sustain contractile function. During acute hypoxic states, the body responds with a compensatory increase in cardiac output that further increase...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:PLoS Biol
Päätekijät: Boehme, Jason, Le Moan, Natacha, Kameny, Rebecca J., Loucks, Alexandra, Johengen, Michael J., Lesneski, Amy L., Gong, Wenhui, Goudy, Brian D., Davis, Tina, Tanaka, Kevin, Davis, Andrew, He, Youping, Long-Boyle, Janel, Ivaturi, Vijay, Gobburu, Jogarao V. S., Winger, Jonathan A., Cary, Stephen P., Datar, Sanjeev A., Fineman, Jeffrey R., Krtolica, Ana, Maltepe, Emin
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Public Library of Science 2018
Aiheet:
Short Reports
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC6193608/
https://ncbi.nlm.nih.gov/pubmed/30335746
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.2005924
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