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Extrinsic Tryptophans as NMR Probes of Allosteric Coupling in Membrane Proteins: Application to the A(2A) Adenosine Receptor
Tryptophan indole (15)N–(1)H signals are well separated in nuclear magnetic resonance (NMR) spectra of proteins. Assignment of the indole (15)N–(1)H signals therefore enables one to obtain site-specific information on complex proteins in supramacromolecular systems, even when extensive assignment of...
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| Publicado no: | J Am Chem Soc |
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| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6192543/ https://ncbi.nlm.nih.gov/pubmed/29874058 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.8b03805 |
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