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NS6740, an α7 nicotinic acetylcholine receptor silent agonist, disrupts hippocampal synaptic plasticity

Long-term potentiation (LTP) in the dentate gyrus was previously shown to be enhanced by nicotine, an effect dependent on both homomeric α7 and heteromeric α2β2 nicotinic acetylcholine receptors (nAChR). In our experiments, bath-applied nicotine produced no significant enhancement of LTP. The α7 nAC...

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Detaylı Bibliyografya
Yayımlandı:Neurosci Lett
Asıl Yazarlar: Papke, Roger L., Peng, Can, Kumar, Ashok, Stokes, Clare
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2018
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6191859/
https://ncbi.nlm.nih.gov/pubmed/29679680
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neulet.2018.04.025
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