Role of Spdef in the Regulation of Muc5b Expression in the Airways of Naive and Mucoobstructed Mice

Understanding how expression of airway secretory mucins MUC5B and MUC5AC is regulated in health and disease is important to elucidating the pathogenesis of mucoobstructive respiratory diseases. The transcription factor SPDEF (sterile α-motif pointed domain epithelial specific transcription factor) i...

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Vydáno v:Am J Respir Cell Mol Biol
Hlavní autoři: Chen, Gang, Volmer, Allison S., Wilkinson, Kristen J., Deng, Yangmei, Jones, Lisa C., Yu, Dongfang, Bustamante-Marin, Ximena M., Burns, Kimberlie A., Grubb, Barbara R., O’Neal, Wanda K., Livraghi-Butrico, Alessandra, Boucher, Richard C.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Thoracic Society 2018
Témata:
Original Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6189647/
https://ncbi.nlm.nih.gov/pubmed/29579396
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2017-0127OC
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