Role of Spdef in the Regulation of Muc5b Expression in the Airways of Naive and Mucoobstructed Mice

Understanding how expression of airway secretory mucins MUC5B and MUC5AC is regulated in health and disease is important to elucidating the pathogenesis of mucoobstructive respiratory diseases. The transcription factor SPDEF (sterile α-motif pointed domain epithelial specific transcription factor) i...

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Detalhes bibliográficos
Publicado no:Am J Respir Cell Mol Biol
Main Authors: Chen, Gang, Volmer, Allison S., Wilkinson, Kristen J., Deng, Yangmei, Jones, Lisa C., Yu, Dongfang, Bustamante-Marin, Ximena M., Burns, Kimberlie A., Grubb, Barbara R., O’Neal, Wanda K., Livraghi-Butrico, Alessandra, Boucher, Richard C.
Formato: Artigo
Idioma:Inglês
Publicado em: American Thoracic Society 2018
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6189647/
https://ncbi.nlm.nih.gov/pubmed/29579396
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2017-0127OC
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