Contribution of mucus concentration and secreted mucins Muc5ac and Muc5b to the pathogenesis of muco-obstructive lung disease

Airway diseases, including cigarette smoke-induced chronic bronchitis, cystic fibrosis, and primary ciliary dyskinesia are associated with decreased mucociliary clearance (MCC). However, it is not known whether a simple reduction in MCC or concentration-dependent mucus adhesion to airway surfaces do...

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Vydáno v:Mucosal Immunol
Hlavní autoři: Livraghi-Butrico, Alessandra, Grubb, Barbara R., Wilkinson, Kristen J., Volmer, Allison S., Burns, Kimberly A., Evans, Christopher M., O'Neal, Wanda K., Boucher, Richard C.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2016
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5250616/
https://ncbi.nlm.nih.gov/pubmed/27435107
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mi.2016.63
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