Epithelial Heparan Sulfate Contributes to Alveolar Barrier Function and Is Shed during Lung Injury

The lung epithelial glycocalyx is a carbohydrate-enriched layer lining the pulmonary epithelial surface. Although epithelial glycocalyx visualization has been reported, its composition and function remain unknown. Using immunofluorescence and mass spectrometry, we identified heparan sulfate (HS) and...

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Dades bibliogràfiques
Publicat a:Am J Respir Cell Mol Biol
Autors principals: Haeger, Sarah M., Liu, Xinyue, Han, Xiaorui, McNeil, J. Brennan, Oshima, Kaori, McMurtry, Sarah A., Yang, Yimu, Ouyang, Yilan, Zhang, Fuming, Nozik-Grayck, Eva, Zemans, Rachel L., Tuder, Rubin M., Bastarache, Julie A., Linhardt, Robert J., Schmidt, Eric P.
Format: Artigo
Idioma:Inglês
Publicat: American Thoracic Society 2018
Matèries:
Original Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6189644/
https://ncbi.nlm.nih.gov/pubmed/29584451
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2017-0428OC
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