Epithelial Heparan Sulfate Contributes to Alveolar Barrier Function and Is Shed during Lung Injury

The lung epithelial glycocalyx is a carbohydrate-enriched layer lining the pulmonary epithelial surface. Although epithelial glycocalyx visualization has been reported, its composition and function remain unknown. Using immunofluorescence and mass spectrometry, we identified heparan sulfate (HS) and...

詳細記述

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書誌詳細
出版年:Am J Respir Cell Mol Biol
主要な著者: Haeger, Sarah M., Liu, Xinyue, Han, Xiaorui, McNeil, J. Brennan, Oshima, Kaori, McMurtry, Sarah A., Yang, Yimu, Ouyang, Yilan, Zhang, Fuming, Nozik-Grayck, Eva, Zemans, Rachel L., Tuder, Rubin M., Bastarache, Julie A., Linhardt, Robert J., Schmidt, Eric P.
フォーマット: Artigo
言語:Inglês
出版事項: American Thoracic Society 2018
主題:
Original Research
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6189644/
https://ncbi.nlm.nih.gov/pubmed/29584451
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2017-0428OC
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