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In Vivo Persistence of Chimeric Virus after Substitution of the Kaposi's Sarcoma-Associated Herpesvirus LANA DNA Binding Domain with That of Murid Herpesvirus 4

The latency-associated nuclear antigen from Kaposi's sarcoma-associated herpesvirus (KSHV), kLANA, and its homolog from the murid herpesvirus 4 (MuHV-4), mLANA, are essential for viral latency. kLANA is nearly four times the size of mLANA, mainly due to an extensive central repeat region that i...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Pires de Miranda, Marta, Quendera, Ana Patrícia, McVey, Colin E., Kaye, Kenneth M., Simas, J. Pedro
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6189500/
https://ncbi.nlm.nih.gov/pubmed/30111565
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01251-18
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