Identification of Kaposi's Sarcoma-Associated Herpesvirus LANA Regions Important for Episome Segregation, Replication, and Persistence

Kaposi's sarcoma-associated herpesvirus (KSHV) latency-associated nuclear antigen (LANA) is a 1,162-amino-acid protein that mediates the maintenance of episomal viral genomes in latently infected cells. The two central components of episome persistence are DNA replication with each cell divisio...

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Detalhes bibliográficos
Main Authors: De León Vázquez, Erika, Carey, Vincent J., Kaye, Kenneth M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2013
Assuntos:
Genome Replication and Regulation of Viral Gene Expression
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3807934/
https://ncbi.nlm.nih.gov/pubmed/24006437
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01243-13
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