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The Internal Kaposi's Sarcoma-Associated Herpesvirus LANA Regions Exert a Critical Role on Episome Persistence

Kaposi's sarcoma-associated herpesvirus (KSHV) latency-associated nuclear antigen (LANA) is a 1,162-amino-acid protein that acts on viral terminal repeat (TR) DNA to mediate KSHV episome persistence. The two essential components of episome persistence are DNA replication prior to cell division...

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Autors principals: De León Vázquez, Erika, Kaye, Kenneth M.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2011
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3147901/
https://ncbi.nlm.nih.gov/pubmed/21593163
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00304-11
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