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BH3-Dependent and Independent Activation of BAX and BAK in Mitochondrial Apoptosis

Mitochondria play key roles in mammalian apoptosis, a highly regulated genetic program of cell suicide. Multiple apoptotic signals culminate in mitochondrial outer membrane permeabilization (MOMP), which not only couples the mitochondria to the activation of caspases but also initiates caspase-indep...

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Dades bibliogràfiques
Publicat a:Curr Opin Physiol
Autors principals: Jeng, Paul S., Inoue-Yamauchi, Akane, Hsieh, James J., Cheng, Emily H.
Format: Artigo
Idioma:Inglês
Publicat: 2018
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6186458/
https://ncbi.nlm.nih.gov/pubmed/30334018
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cophys.2018.03.005
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