Cycloheximide Can Induce Bax/Bak Dependent Myeloid Cell Death Independently of Multiple BH3-Only Proteins

Apoptosis mediated by Bax or Bak is usually thought to be triggered by BH3-only members of the Bcl-2 protein family. BH3-only proteins can directly bind to and activate Bax or Bak, or indirectly activate them by binding to anti-apoptotic Bcl-2 family members, thereby relieving their inhibition of Ba...

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Publicat a:PLoS One
Autors principals: Goodall, Katharine J., Finch-Edmondson, Megan L., van Vuuren, Joanne, Yeoh, George C., Gentle, Ian E., Vince, James E., Ekert, Paul G., Vaux, David L., Callus, Bernard A.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2016
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5091851/
https://ncbi.nlm.nih.gov/pubmed/27806040
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0164003
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