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Sirtuin-3 modulates Bak- and Bax-dependent apoptosis
Sirtuin-3 exhibits properties of a tumor suppressor partly emanating from its ability to control the state of mitochondrial metabolism, with depletion of sirt-3 increasing tumor cell survival. In the present study we demonstrate that depletion of sirtuin-3 brings about an anti-apoptotic phenotype vi...
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| Autori principali: | , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
The Company of Biologists
2013
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3603519/ https://ncbi.nlm.nih.gov/pubmed/23108666 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.115188 |
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