Impact of Variable RNA-Sequencing Depth on Gene Expression Signatures and Target Compound Robustness: Case Study Examining Brain Tumor (Glioma) Disease Progression

PURPOSE: Gene expression profiling can uncover biologic mechanisms underlying disease and is important in drug development. RNA sequencing (RNA-seq) is routinely used to assess gene expression, but costs remain high. Sample multiplexing reduces RNA-seq costs; however, multiplexed samples have lower...

Descripció completa

Guardat en:
Dades bibliogràfiques
Publicat a:JCO Precis Oncol
Autors principals: Stupnikov, Alexey, O’Reilly, Paul G., McInerney, Caitriona E., Roddy, Aideen C., Dunne, Philip D., Gilmore, Alan, Ellis, Hayley P., Flannery, Tom, Healy, Estelle, McIntosh, Stuart A., Savage, Kienan, Kurian, Kathreena M., Emmert-Streib, Frank, Prise, Kevin M., Salto-Tellez, Manuel, McArt, Darragh G.
Format: Artigo
Idioma:Inglês
Publicat: American Society of Clinical Oncology 2018
Matèries:
Original Report
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6186166/
https://ncbi.nlm.nih.gov/pubmed/30324181
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1200/PO.18.00014
Etiquetes: Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!

Ítems similars