GENOMIC PROFILING OF PRIMARY AND MATCHED RECURRENT GLIOBLASTOMA TUMOURS REVEALS THAT THE MUTATIONAL LANDSCAPE INCLUDES CLINICALLY ACTIONABLE VARIATION

Glioblastomas account for 90% of adult brain tumours and patient survival remains low. Understanding genetic alterations in subtypes could improve therapeutic intervention. Tumours from 41 patients, 8 with matched recurrent glioblastomas were genomically profiled for 130 neuro-oncology genes using a...

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Detalhes bibliográficos
Publicado no:Neuro Oncol
Main Authors: McInerney, Caitríona, Ellis, Hayley, Schrinpf, Daniel, Sahm, Felix, Stupnikov, Alexei, Wadsley, Marc, Wragg, Christopher, White, Paul, McArt, Darragh, Kurian, Kathreena
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6168815/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noy129.034
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