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Simulations and Experiments Delineate Amyloid Fibrilization by Peptides Derived from Glaucoma-associated Myocilin
Mutant myocilin aggregation is associated with inherited open angle glaucoma, a prevalent optic neuropathy leading to blindness. Comprehension of mutant myocilin aggregation is of fundamental importance to glaucoma pathogenesis and ties glaucoma to amyloid diseases such as Alzheimer’s. Here we probe...
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| 發表在: | J Phys Chem B |
|---|---|
| Main Authors: | , , , , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
2018
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6186006/ https://ncbi.nlm.nih.gov/pubmed/29724098 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jpcb.8b03000 |
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