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Amyloid fibril formation by the glaucoma-associated olfactomedin domain of myocilin

Myocilin is a protein found in the extracellular matrix of the trabecular meshwork (TM) tissue, the anatomical region of the eye involved in regulating intraocular pressure. Wild-type (WT) myocilin has been associated with steroid-induced glaucoma, and variants of myocilin have been linked to early-...

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Autors principals: Orwig, Susan D., Perry, Christopher W., Kim, Laura Y., Turnage, Katherine C., Zhang, Rong, Vollrath, Douglas, Schmidt-Krey, Ingeborg, Lieberman, Raquel L.
Format: Artigo
Idioma:Inglês
Publicat: 2011
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3323732/
https://ncbi.nlm.nih.gov/pubmed/22197377
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2011.12.016
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