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Biophysical Characterization of the Olfactomedin Domain of Myocilin, an Extracellular Matrix Protein Implicated in Inherited Forms of Glaucoma

Myocilin is an eye protein found in the trabecular extracellular matrix (TEM), within the anatomic region that controls fluid flow. Variants of myocilin, localized to its olfactomedin (OLF) domain, have been linked to inherited forms of glaucoma, a disease associated with elevated intraocular pressu...

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Autors principals: Orwig, Susan D., Lieberman, Raquel L.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2011
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3026022/
https://ncbi.nlm.nih.gov/pubmed/21283635
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0016347
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