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The Glaucoma-associated Olfactomedin Domain of Myocilin Is a Novel Calcium Binding Protein
Myocilin is a protein found in the trabecular meshwork extracellular matrix tissue of the eye that plays a role in regulating intraocular pressure. Both wild-type and certain myocilin variants containing mutations in the olfactomedin (OLF) domain are linked to the optic neuropathy glaucoma. Because...
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| Главные авторы: | , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
American Society for Biochemistry and Molecular Biology
2012
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3527924/ https://ncbi.nlm.nih.gov/pubmed/23129764 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.408906 |
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