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Amyloid fibril formation by the glaucoma-associated olfactomedin domain of myocilin
Myocilin is a protein found in the extracellular matrix of the trabecular meshwork (TM) tissue, the anatomical region of the eye involved in regulating intraocular pressure. Wild-type (WT) myocilin has been associated with steroid-induced glaucoma, and variants of myocilin have been linked to early-...
Shranjeno v:
| Main Authors: | , , , , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2011
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3323732/ https://ncbi.nlm.nih.gov/pubmed/22197377 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2011.12.016 |
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