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Simulations and Experiments Delineate Amyloid Fibrilization by Peptides Derived from Glaucoma-associated Myocilin

Mutant myocilin aggregation is associated with inherited open angle glaucoma, a prevalent optic neuropathy leading to blindness. Comprehension of mutant myocilin aggregation is of fundamental importance to glaucoma pathogenesis and ties glaucoma to amyloid diseases such as Alzheimer’s. Here we probe...

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Xehetasun bibliografikoak
Argitaratua izan da:J Phys Chem B
Egile Nagusiak: Wang, Yiming, Gao, Yuan, Hill, Shannon E., Huard, Dustin J. E., Tomlin, Moya O., Lieberman, Raquel L., Paravastu, Anant K., Hall, Carol K.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2018
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6186006/
https://ncbi.nlm.nih.gov/pubmed/29724098
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jpcb.8b03000
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