bcSeq: an R package for fast sequence mapping in high-throughput shRNA and CRISPR screens

SUMMARY: CRISPR-Cas9 and shRNA high-throughput sequencing screens have abundant applications for basic and translational research. Methods and tools for the analysis of these screens must properly account for sequencing error, resolve ambiguous mappings among similar sequences in the barcode library...

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Bibliografski detalji
Izdano u:Bioinformatics
Glavni autori: Lin, Jiaxing, Gresham, Jeremy, Wang, Tongrong, Kim, So Young, Alvarez, James, Damrauer, Jeffrey S, Floyd, Scott, Granek, Joshua, Allen, Andrew, Chan, Cliburn, Xie, Jichun, Owzar, Kouros
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2018
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Applications Notes
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6184561/
https://ncbi.nlm.nih.gov/pubmed/29790906
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/bty402
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