edgeR: a versatile tool for the analysis of shRNA-seq and CRISPR-Cas9 genetic screens

Pooled library sequencing screens that perturb gene function in a high-throughput manner are becoming increasingly popular in functional genomics research. Irrespective of the mechanism by which loss of function is achieved, via either RNA interference using short hairpin RNAs (shRNAs) or genetic mu...

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Hlavní autoři: Dai, Zhiyin, Sheridan, Julie M., Gearing, Linden J., Moore, Darcy L., Su, Shian, Wormald, Sam, Wilcox, Stephen, O'Connor, Liam, Dickins, Ross A., Blewitt, Marnie E., Ritchie, Matthew E.
Médium: Artigo
Jazyk:Inglês
Vydáno: F1000Research 2014
Témata:
Software Tool Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4023662/
https://ncbi.nlm.nih.gov/pubmed/24860646
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.12688/f1000research.3928.2
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