A pooled shRNA screen for regulators of primary mammary stem and progenitor cells identifies roles for Asap1 and Prox1

BACKGROUND: The molecular regulators that orchestrate stem cell renewal, proliferation and differentiation along the mammary epithelial hierarchy remain poorly understood. Here we have performed a large-scale pooled RNAi screen in primary mouse mammary stem cell (MaSC)-enriched basal cells using 129...

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Detalhes bibliográficos
Publicado no:BMC Cancer
Main Authors: Sheridan, Julie M, Ritchie, Matthew E, Best, Sarah A, Jiang, Kun, Beck, Tamara J, Vaillant, François, Liu, Kevin, Dickins, Ross A, Smyth, Gordon K, Lindeman, Geoffrey J, Visvader, Jane E
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4399223/
https://ncbi.nlm.nih.gov/pubmed/25879659
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-015-1187-z
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