bcSeq: an R package for fast sequence mapping in high-throughput shRNA and CRISPR screens

SUMMARY: CRISPR-Cas9 and shRNA high-throughput sequencing screens have abundant applications for basic and translational research. Methods and tools for the analysis of these screens must properly account for sequencing error, resolve ambiguous mappings among similar sequences in the barcode library...

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Veröffentlicht in:Bioinformatics
Hauptverfasser: Lin, Jiaxing, Gresham, Jeremy, Wang, Tongrong, Kim, So Young, Alvarez, James, Damrauer, Jeffrey S, Floyd, Scott, Granek, Joshua, Allen, Andrew, Chan, Cliburn, Xie, Jichun, Owzar, Kouros
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2018
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6184561/
https://ncbi.nlm.nih.gov/pubmed/29790906
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/bty402
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