bcSeq: an R package for fast sequence mapping in high-throughput shRNA and CRISPR screens

SUMMARY: CRISPR-Cas9 and shRNA high-throughput sequencing screens have abundant applications for basic and translational research. Methods and tools for the analysis of these screens must properly account for sequencing error, resolve ambiguous mappings among similar sequences in the barcode library...

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Detalhes bibliográficos
Publicado no:Bioinformatics
Main Authors: Lin, Jiaxing, Gresham, Jeremy, Wang, Tongrong, Kim, So Young, Alvarez, James, Damrauer, Jeffrey S, Floyd, Scott, Granek, Joshua, Allen, Andrew, Chan, Cliburn, Xie, Jichun, Owzar, Kouros
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2018
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Applications Notes
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6184561/
https://ncbi.nlm.nih.gov/pubmed/29790906
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/bty402
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