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THE REGULATION OF T CELL SENESCENCE AND METABOLISM BY P38 MAPKINASE SIGNALING

Persistent viral infections, ageing and inflammatory syndromes induce the accumulation of senescent human T cells. However the mechanism that regulates the function of these end-stage cells is unclear. Human CD8(+) effector memory T cells that re-express CD45RA (CD27(-)CD45RA(+); EMRA) express surfa...

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Publicado en:Innov Aging
Autores principales: Lanna, A., Henson, S.M., Akbar, A.
Formato: Artigo
Lenguaje:Inglês
Publicado: Oxford University Press 2017
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6183675/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/geroni/igx004.4558
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