Human CD8(+) EMRA T cells display a senescence‐associated secretory phenotype regulated by p38 MAPK

Cellular senescence is accompanied by a senescence‐associated secretory phenotype (SASP). We show here that primary human senescent CD8(+) T cells also display a SASP comprising chemokines, cytokines and extracellular matrix remodelling proteases that are unique to this subset and contribute to age‐...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Aging Cell
Main Authors: Callender, Lauren A., Carroll, Elizabeth C., Beal, Robert W. J., Chambers, Emma S., Nourshargh, Sussan, Akbar, Arne N., Henson, Sian M.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2017
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5770853/
https://ncbi.nlm.nih.gov/pubmed/29024417
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acel.12675
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados