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p38MAPK is a novel DNA damage response-independent regulator of the senescence-associated secretory phenotype

Cellular senescence suppresses cancer by forcing potentially oncogenic cells into a permanent cell cycle arrest. Senescent cells also secrete growth factors, proteases, and inflammatory cytokines, termed the senescence-associated secretory phenotype (SASP). Much is known about pathways that regulate...

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Detalhes bibliográficos
Main Authors: Freund, Adam, Patil, Christopher K, Campisi, Judith
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3102277/
https://ncbi.nlm.nih.gov/pubmed/21399611
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2011.69
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