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Cellular senescence and the senescent secretory phenotype: therapeutic opportunities

Aging is the largest risk factor for most chronic diseases, which account for the majority of morbidity and health care expenditures in developed nations. New findings suggest that aging is a modifiable risk factor, and it may be feasible to delay age-related diseases as a group by modulating fundam...

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Bibliografiske detaljer
Main Authors: Tchkonia, Tamara, Zhu, Yi, van Deursen, Jan, Campisi, Judith, Kirkland, James L.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Clinical Investigation 2013
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3582125/
https://ncbi.nlm.nih.gov/pubmed/23454759
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI64098
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