Mitochondrial Dysfunction Induces Senescence with a Distinct Secretory Phenotype

Cellular senescence permanently arrests cell proliferation, often accompanied by a multi-faceted senescence-associated secretory phenotype (SASP). Loss of mitochondrial function can drive age-related declines in the function of many post-mitotic tissues, but little is known about how mitochondrial d...

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Detalhes bibliográficos
Publicado no:Cell Metab
Main Authors: Wiley, Christopher D., Velarde, Michael C., Lecot, Pacome, Liu, Su, Sarnoski, Ethan A., Freund, Adam, Shirakawa, Kotaro, Lim, Hyung W., Davis, Sonnet S., Ramanathan, Arvind, Gerencser, Akos A., Verdin, Eric, Campisi, Judith
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4749409/
https://ncbi.nlm.nih.gov/pubmed/26686024
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cmet.2015.11.011
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