Mitochondrial Dysfunction Induces Senescence with a Distinct Secretory Phenotype

Cellular senescence permanently arrests cell proliferation, often accompanied by a multi-faceted senescence-associated secretory phenotype (SASP). Loss of mitochondrial function can drive age-related declines in the function of many post-mitotic tissues, but little is known about how mitochondrial d...

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Опубликовано в: :Cell Metab
Главные авторы: Wiley, Christopher D., Velarde, Michael C., Lecot, Pacome, Liu, Su, Sarnoski, Ethan A., Freund, Adam, Shirakawa, Kotaro, Lim, Hyung W., Davis, Sonnet S., Ramanathan, Arvind, Gerencser, Akos A., Verdin, Eric, Campisi, Judith
Формат: Artigo
Язык:Inglês
Опубликовано: 2015
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Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4749409/
https://ncbi.nlm.nih.gov/pubmed/26686024
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cmet.2015.11.011
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