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Mitochondrial Dysfunction Induces Senescence with a Distinct Secretory Phenotype

Cellular senescence permanently arrests cell proliferation, often accompanied by a multi-faceted senescence-associated secretory phenotype (SASP). Loss of mitochondrial function can drive age-related declines in the function of many post-mitotic tissues, but little is known about how mitochondrial d...

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Bibliografski detalji
Izdano u:Cell Metab
Glavni autori: Wiley, Christopher D., Velarde, Michael C., Lecot, Pacome, Liu, Su, Sarnoski, Ethan A., Freund, Adam, Shirakawa, Kotaro, Lim, Hyung W., Davis, Sonnet S., Ramanathan, Arvind, Gerencser, Akos A., Verdin, Eric, Campisi, Judith
Format: Artigo
Jezik:Inglês
Izdano: 2015
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4749409/
https://ncbi.nlm.nih.gov/pubmed/26686024
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cmet.2015.11.011
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