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Context-dependent effects of cellular senescence in cancer development

Cellular senescence is an established tumour-suppressive mechanism that prevents the proliferation of premalignant cells. However, several lines of evidence show that senescent cells, which often persist in vivo, can also promote tumour progression in addition to other age-related pathologies via th...

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Podrobná bibliografie
Vydáno v:Br J Cancer
Hlavní autoři: Lecot, Pacome, Alimirah, Fatouma, Desprez, Pierre-Yves, Campisi, Judith, Wiley, Christopher
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2016
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4891501/
https://ncbi.nlm.nih.gov/pubmed/27140310
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjc.2016.115
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