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Context-dependent effects of cellular senescence in cancer development

Cellular senescence is an established tumour-suppressive mechanism that prevents the proliferation of premalignant cells. However, several lines of evidence show that senescent cells, which often persist in vivo, can also promote tumour progression in addition to other age-related pathologies via th...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Br J Cancer
Egile Nagusiak: Lecot, Pacome, Alimirah, Fatouma, Desprez, Pierre-Yves, Campisi, Judith, Wiley, Christopher
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Nature Publishing Group 2016
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4891501/
https://ncbi.nlm.nih.gov/pubmed/27140310
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjc.2016.115
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