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Context-dependent effects of cellular senescence in cancer development
Cellular senescence is an established tumour-suppressive mechanism that prevents the proliferation of premalignant cells. However, several lines of evidence show that senescent cells, which often persist in vivo, can also promote tumour progression in addition to other age-related pathologies via th...
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| 發表在: | Br J Cancer |
|---|---|
| Main Authors: | , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Nature Publishing Group
2016
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4891501/ https://ncbi.nlm.nih.gov/pubmed/27140310 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjc.2016.115 |
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