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The 3′-end region of the human PDGFR-β core promoter nuclease hypersensitive element forms a mixture of two unique end-insertion G-quadruplexes

BACKGROUND: While the most stable G-quadruplex formed in the human PDGFR-β promoter nuclease hypersensitive element (NHE) is the 5′-mid G-quadruplex, the 3′-end sequence that contains a 3′-GGA run forms a less stable G-quadruplex. Recently, the 3′-end G-quadruplex was found to be a transcriptional r...

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Detalhes bibliográficos
Publicado no:Biochim Biophys Acta Gen Subj
Main Authors: Onel, Buket, Carver, Megan, Agrawal, Prashansa, Hurley, Laurence H., Yang, Danzhou
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6183060/
https://ncbi.nlm.nih.gov/pubmed/29288770
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbagen.2017.12.011
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