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Solution structure of the major G-quadruplex formed in the human VEGF promoter in K(+): insights into loop interactions of the parallel G-quadruplexes

Vascular endothelial growth factor (VEGF) proximal promoter region contains a poly G/C-rich element that is essential for basal and inducible VEGF expression. The guanine-rich strand on this tract has been shown to form the DNA G-quadruplex structure, whose stabilization by small molecules can suppr...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Agrawal, Prashansa, Hatzakis, Emmanuel, Guo, Kexiao, Carver, Megan, Yang, Danzhou
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Oxford University Press 2013
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3905851/
https://ncbi.nlm.nih.gov/pubmed/24005038
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkt784
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