Effects of diets enriched in linoleic acid and its peroxidation products on brain fatty acids, oxylipins, and aldehydes in mice

BACKGROUND: Linoleic acid (LA) is abundant in modern industrialized diets. Oxidized LA metabolites (OXLAMs) and reactive aldehydes, such as 4-hydroxy-2-nonenal (4-HNE), are present in heated vegetable oils and can be endogenously synthesized following consumption of dietary LA. OXLAMs have been impl...

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Veröffentlicht in:Biochim Biophys Acta Mol Cell Biol Lipids
Hauptverfasser: Ramsden, Christopher E., Hennebelle, Marie, Schuster, Susanne, Keyes, Gregory S., Johnson, Casey D., Kirpich, Irina A., Dahlen, Jeff E., Horowitz, Mark S., Zamora, Daisy, Feldstein, Ariel E., McClain, Craig J., Muhlhausler, Beverly S., Makrides, Maria, Gibson, Robert A., Taha, Ameer Y.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2018
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6180905/
https://ncbi.nlm.nih.gov/pubmed/30053599
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbalip.2018.07.007
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