Dietary Linoleic Acid and Its Oxidized Metabolites Exacerbate Liver Injury Caused by Ethanol via Induction of Hepatic Proinflammatory Response in Mice

Alcoholic liver disease is a major human health problem leading to significant morbidity and mortality in the United States and worldwide. Dietary fat plays an important role in alcoholic liver disease pathogenesis. Herein, we tested the hypothesis that a combination of ethanol and a diet rich in li...

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Publicado en:Am J Pathol
Autores principales: Warner, Dennis R., Liu, Huilin, Miller, Matthew E., Ramsden, Christopher E., Gao, Bin, Feldstein, Ariel E., Schuster, Susanne, McClain, Craig J., Kirpich, Irina A.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Investigative Pathology 2017
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5808136/
https://ncbi.nlm.nih.gov/pubmed/28923202
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2017.06.008
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