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Dietary Linoleic Acid and Its Oxidized Metabolites Exacerbate Liver Injury Caused by Ethanol via Induction of Hepatic Proinflammatory Response in Mice

Alcoholic liver disease is a major human health problem leading to significant morbidity and mortality in the United States and worldwide. Dietary fat plays an important role in alcoholic liver disease pathogenesis. Herein, we tested the hypothesis that a combination of ethanol and a diet rich in li...

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Detalhes bibliográficos
Publicado no:Am J Pathol
Main Authors: Warner, Dennis R., Liu, Huilin, Miller, Matthew E., Ramsden, Christopher E., Gao, Bin, Feldstein, Ariel E., Schuster, Susanne, McClain, Craig J., Kirpich, Irina A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5808136/
https://ncbi.nlm.nih.gov/pubmed/28923202
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2017.06.008
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