Dietary Linoleic Acid and Its Oxidized Metabolites Exacerbate Liver Injury Caused by Ethanol via Induction of Hepatic Proinflammatory Response in Mice

Alcoholic liver disease is a major human health problem leading to significant morbidity and mortality in the United States and worldwide. Dietary fat plays an important role in alcoholic liver disease pathogenesis. Herein, we tested the hypothesis that a combination of ethanol and a diet rich in li...

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Publicat a:Am J Pathol
Autors principals: Warner, Dennis R., Liu, Huilin, Miller, Matthew E., Ramsden, Christopher E., Gao, Bin, Feldstein, Ariel E., Schuster, Susanne, McClain, Craig J., Kirpich, Irina A.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Investigative Pathology 2017
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5808136/
https://ncbi.nlm.nih.gov/pubmed/28923202
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2017.06.008
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