Optimization of fermentation conditions for an Escherichia coli strain engineered using the response surface method to produce a novel therapeutic DNA vaccine for rheumatoid arthritis

BACKGROUND: Fermentation condition optimization and nutrients screening are of equal importance for efficient production of plasmid DNA vaccines. This directly affects the downstream purification and final quality and yield of plasmid DNA vaccines. The present study aimed to optimize the fermentatio...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:J Biol Eng
Päätekijät: Long, Juan, Zhao, Xiao, Liang, Fei, Liu, Nan, Sun, Yuying, Xi, Yongzhi
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: BioMed Central 2018
Aiheet:
Research
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC6180442/
https://ncbi.nlm.nih.gov/pubmed/30337953
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13036-018-0110-y
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