Dynamic profiles, biodistribution and integration evaluation after intramuscular/intravenous delivery of a novel therapeutic DNA vaccine encoding chicken type II collagen for rheumatoid arthritis in vaccinated normal rodent

BACKGROUND: The persistence, biodistribution, and risk of integration into the host genome of any new therapeutic DNA vaccine must be established in preclinical studies. We previously developed the DNA vaccine pcDNA-CCOL2A1 encoding chicken type II collagen (CCII) for the treatment of rheumatoid art...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:J Nanobiotechnology
Main Authors: Zhao, Xiao, Long, Juan, Liang, Fei, Liu, Nan, Sun, Yuying, Xi, Yongzhi
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2019
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6729025/
https://ncbi.nlm.nih.gov/pubmed/31492169
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12951-019-0528-5
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados