Dynamic profiles, biodistribution and integration evaluation after intramuscular/intravenous delivery of a novel therapeutic DNA vaccine encoding chicken type II collagen for rheumatoid arthritis in vaccinated normal rodent

BACKGROUND: The persistence, biodistribution, and risk of integration into the host genome of any new therapeutic DNA vaccine must be established in preclinical studies. We previously developed the DNA vaccine pcDNA-CCOL2A1 encoding chicken type II collagen (CCII) for the treatment of rheumatoid art...

Ful tanımlama

Kaydedildi:
Detaylı Bibliyografya
Yayımlandı:J Nanobiotechnology
Asıl Yazarlar: Zhao, Xiao, Long, Juan, Liang, Fei, Liu, Nan, Sun, Yuying, Xi, Yongzhi
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: BioMed Central 2019
Konular:
Research
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6729025/
https://ncbi.nlm.nih.gov/pubmed/31492169
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12951-019-0528-5
Etiketler: Etiketle
Etiket eklenmemiş, İlk siz ekleyin!

Benzer Materyaller