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Safety and immunogenicity of a novel therapeutic DNA vaccine encoding chicken type II collagen for rheumatoid arthritis in normal rats

Current clinically available treatments for rheumatoid arthritis (RA) fail to cure the disease or unsatisfactorily halt disease progression. To overcome these limitations, the development of therapeutic DNA vaccines and boosters may offer new promising strategies. Because type II collagen (CII) as a...

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Detalhes bibliográficos
Publicado no:Hum Vaccin Immunother
Main Authors: Juan, Long, Xiao, Zhao, Song, Yun, Zhijian, Zhang, Jing, Jin, Kun, Yu, Yuna, Hao, Dongfa, Dai, Lili, Ding, Liuxin, Tan, Fei, Liang, Nan, Liu, Fang, Yuan, Yuying, Sun, Yongzhi, Xi
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5054790/
https://ncbi.nlm.nih.gov/pubmed/26697972
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/21645515.2015.1073425
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