Optimization of fermentation conditions for an Escherichia coli strain engineered using the response surface method to produce a novel therapeutic DNA vaccine for rheumatoid arthritis

BACKGROUND: Fermentation condition optimization and nutrients screening are of equal importance for efficient production of plasmid DNA vaccines. This directly affects the downstream purification and final quality and yield of plasmid DNA vaccines. The present study aimed to optimize the fermentatio...

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Detaylı Bibliyografya
Yayımlandı:J Biol Eng
Asıl Yazarlar: Long, Juan, Zhao, Xiao, Liang, Fei, Liu, Nan, Sun, Yuying, Xi, Yongzhi
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: BioMed Central 2018
Konular:
Research
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6180442/
https://ncbi.nlm.nih.gov/pubmed/30337953
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13036-018-0110-y
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