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MDMX under stress: the MDMX-MDM2 complex as stress signals hub

The tumor suppressor p53 plays a central role in safeguarding cellular homeostasis. Upon various types of stress signals such as DNA damage or oncogenic stress, p53 is promptly activated to prevent and repair damages that can threaten the genome stability. The two major negative regulators of p53 ar...

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Bibliografski detalji
Izdano u:Transl Cancer Res
Glavni autori: de Polo, Anna, Vivekanandan, Varunika, Little, John B., Yuan, Zhi-Min
Format: Artigo
Jezik:Inglês
Izdano: 2016
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6178224/
https://ncbi.nlm.nih.gov/pubmed/30319942
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.21037/tcr.2016.12.18
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