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MDMX under stress: the MDMX-MDM2 complex as stress signals hub
The tumor suppressor p53 plays a central role in safeguarding cellular homeostasis. Upon various types of stress signals such as DNA damage or oncogenic stress, p53 is promptly activated to prevent and repair damages that can threaten the genome stability. The two major negative regulators of p53 ar...
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| Vydáno v: | Transl Cancer Res |
|---|---|
| Hlavní autoři: | , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
2016
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6178224/ https://ncbi.nlm.nih.gov/pubmed/30319942 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.21037/tcr.2016.12.18 |
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