Human epidermal growth factor receptor 4 (Her4) Suppresses p53 Protein via Targeting the MDMX-MDM2 Protein Complex: IMPLICATION OF A NOVEL MDMX SER-314 PHOSPHOSITE

Deregulated receptor tyrosine kinase (RTK) signaling is frequently associated with tumorigenesis and therapy resistance, but its underlying mechanisms still need to be elucidated. In this study, we have shown that the RTK human epidermal growth factor receptor 4 (Her4, also known as Erbb4) can inhib...

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Bibliografiske detaljer
Udgivet i:J Biol Chem
Main Authors: Gerarduzzi, Casimiro, de Polo, Anna, Liu, Xue-Song, El Kharbili, Manale, Little, John B., Yuan, Zhi-Min
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2016
Fag:
Cell Biology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5207067/
https://ncbi.nlm.nih.gov/pubmed/27777309
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.752303
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